Run Smoother Trials. Reduce Dropouts. Accelerate Completion.
iSWITCHED is an innovative digital tool designed to facilitate seamless switching between antipsychotics in clinical trials. By minimising dropout rates and ensuring adherence to protocols, it enhances the reliability of clinical trial outcomes. Additionally, iSWITCHED streamlines trial processes, making it an essential resource for studies that require switching antipsychotics or generating real-world evidence.
Simplify Antipsychotic Switching for Seamless Trials
At iSWITCHED, we recognise the operational and financial challenges faced by Contract Research Organisations (CROs) in managing antipsychotic switching during clinical trials of newer antipsychotics. Designed with input from clinicians, trial sponsors, and researchers, our innovative digital tool simplifies the switching process, ensuring smoother trials and faster regulatory success.
iSWITCHED offers customisable protocols, risk assessment tools, and real-time data insights that reduce dropout rates streamline reporting and improve trial consistency. By embedding structured switching management into trial workflows, we help sponsors deliver high-quality data and achieve timely approvals.
The Problem
Clinical trials of newer antipsychotics often involve switching patients from their current antipsychotic to the investigational drug, typically through carefully managed titration protocols, to assess efficacy, safety, and tolerability improvements over existing treatments. For CROs, overseeing antipsychotic switching in clinical trials can be a costly and risky endeavour that affects timelines, compliance, and regulatory success.
High Dropout Rates: Switching-related issues, including adverse events, cause patients to drop out, leading to recruitment delays, re-enrolment costs, and incomplete data.
Trial Delays and Cost Overruns: Dropouts, protocol deviations, and site-level inconsistencies result in costly delays.
Inconsistent Protocols for Switching: Trial sites often interpret switching processes differently due to a lack of standardised processes, leading to protocol deviations, adverse events, and unreliable data.
Lack of Real-World Evidence: Variability in switching and patient non-compliance make it difficult to generate reliable data to support regulatory submissions.
Administrative Burden: Generating reports, tracking compliance, and documenting deviations is an error-prone process that consumes valuable time and resources.
Our Solution
iSWITCHED provides a comprehensive switching management system that empowers trial sponsors and CROs to overcome these challenges, delivering faster and more consistent trial completion: